Impaired transverse patterning in human amnesia is a special case of impaired memory for two-choice discrimination tasks

Citation
Jm. Reed et Lr. Squire, Impaired transverse patterning in human amnesia is a special case of impaired memory for two-choice discrimination tasks, BEHAV NEURO, 113(1), 1999, pp. 3-9
Citations number
54
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BEHAVIORAL NEUROSCIENCE
ISSN journal
07357044 → ACNP
Volume
113
Issue
1
Year of publication
1999
Pages
3 - 9
Database
ISI
SICI code
0735-7044(199902)113:1<3:ITPIHA>2.0.ZU;2-R
Abstract
Three amnesic patients with damage limited to the hippocampal formation, a severely amnesic patient with extensive medial temporal lobe damage, and 9 controls were tested on the transverse patterning problem (A + B-, B + C-, and C + A-) and also on 2 control problems. One of the control problems was matched to the transverse patterning problem with respect to the number of pairwise decisions that were required. The 2nd control problem was matched to the transverse patterning problem with respect to the number of trials needed by controls to learn the task. The amnesic patients were impaired at solving both the: transverse patterning problem and the control problems. The findings suggest that impaired learning of the transverse patterning pr oblem by amnesic patients derives from their general impairment in declarat ive memory, which affects performance on most 2-choice discrimination tasks .