Screening hypochromism of chromophores in macromolecular biostructures

The regular arrangement of chromophores in macromolecules and clusters at d istances less than the wavelength leads to the effect of screening hypochro mism. This effect is due to a fall in the mean absorption probability, i.e. , the mutual shielding of chromophores from light in the competition for a given photon. In macromolecular biostructures, this effect, together with o ther factors, can cause a decrease in the molar absorption coefficient; how ever, using the screening model alone, it is possible to predict the hyperc hromism of oligonucleotides DNA, proteins, aggregates of aromatic hydrocarb ons; and some other structures.