Pg. Agostoni et al., OXYGEN-TRANSPORT TO MUSCLE DURING EXERCISE IN CHRONIC CONGESTIVE-HEART-FAILURE SECONDARY TO IDIOPATHIC DILATED CARDIOMYOPATHY, The American journal of cardiology, 79(8), 1997, pp. 1120
In chronic heart failure, oxygen delivery during exercise is impaired
mainly because of failure of cardiac output to increase normally. Comp
ensatory mechanisms are hemoglobin concentration increase, right-ward
shift in the oxyhemoglobin dissociation curve, and blood flow redistri
bution from the nonexercising organs to the exercising muscles.