The standard treatment of left main coronary artery (LMCA) disease has been
bypass surgery (CABG). Recent reports suggested that stenting of LMCA dise
ase might be feasible. From January 1995 to April 1998, we carried out a pr
ospective study of elective stenting of unprotected LMCA disease to evaluat
e its immediate and long-term results. Of 61 consecutive patients with unpr
otected LMCA disease, 6 were excluded. Acute procedural success was 100% fo
r the remaining 55 patients, without any complications such as stent thromb
osis, myocardial infarction, CABG, or death. During a mean follow-up of 16.
1 +/- 9.6 months, 11 patients (20%) had symptomatic recurrence, between 2 t
o 6 months after their procedure. Seven patients underwent CABG, two had re
peat intervention, one continued with medical therapy, and one died before
planned angiography. There was no late sudden death, Forty-four patients (8
0%) remained asymptomatic. We conclude that elective stenting may be a safe
alternative to CABG in unprotected LMCA disease. (C) 1999 Wiley-Liss, Inc.