The objectives of this study was to test the feasibility and safety of tran
sradial coronary intervention (TRI) in Japanese patients, We compared the r
esults of TRI in 1,791 lesions (1,360 patients) between November 1995 and D
ecember 1997 with those of transfemoral coronary intervention (TFI) in 966
lesions (793 patients) between April and October 1995. We also examined the
radial artery pulse in 294 patients 1-2 weeks after TRI by palpation and D
oppler examination. Arterial puncture, coronary artery cannulation, lesion,
and patient success rates were similar in both groups. No significant diff
erence was noted in the major complication rate. Local complications were s
ignificantly lower in the TRI group (0.3% vs. 3.3%, P < 0.001). Doppler stu
dies of the radial artery were performed in 294 patients chosen at random,
In the first 234 patients, the sheath was pulled out 3 hr after the procedu
re, and in the last 60 patients, immediately after the procedure; radial ar
tery occlusion rates were 5% and 0%, respectively, In conclusion, TRI seems
safe and feasible in Japanese patients. (C) 1999 Wiley-Liss, Inc.