Lk. Michalis et al., Use of vibrational angioplasty for the treatment of chronic total coronaryocclusions: Preliminary results, CATHET C IN, 46(1), 1999, pp. 98-104
The aim of the study was to investigate the feasibility and clinical safety
of vibrational angioplasty in the treatment of chronic total coronary occl
usions and evaluate the clinical and angiographic factors that are predicti
ve of the procedural success and complications of the procedure. Seventy-ei
ght patients with chronic total occlusions (>3 months) resistant to convent
ional techniques were treated by vibrational angioplasty using a variety of
conventional guidewires. Lesions were successfully crossed in 67 (85.9%) c
ases and antegrade flow was achieved in 59 (75.5%). Major complications (my
ocardial infarction and tamponade) occurred in two (2.5%) patients, but no
fatalities ensued. Angiographically detectable dissections were seen in 23
(29.5%) patients but only resulted in vessel compromise and reclosure in 5
cases. Multiple stepwise logistic regression analysis identified the durati
on (<6 months, P = 0.008) and the length of the occlusion (<15 mm, P = 0.03
) as independent predictors of final success and the age of the patient (<5
5 years, P = 0.006) as the only independent predictor of procedural complic
ations. Vibrational angioplasty is a safe technique useful in the treatment
of chronic coronary occlusive disease. Patients in whom the procedure is l
ikely to prove most successful may be easily identified by clinical and ang
iographic features (duration and length of occlusion). (C) 1999 Wiley-Liss,
Inc.