In an earlier study, Dellatolas, Curt and Lellouch (1991) concluded that ha
ndedness is not related to season of birth. However, post-hoc exploration o
f their and other sets of data has shown that there is an apparent tendency
for left-handedness to be more prevalent in the period March-July than in
the period August-February. The present work tested this seasonal hypothesi
s prospectively among university students. It was found that the proportion
of all left-handed participants who were born in the period March-July was
indeed significantly greater than the proportion of all right-handed parti
cipants who were born in the same period. Furthermore, the pattern of seaso
nal influence upon handedness did not vary significantly between females an
d males. The relation between handedness and season of birth may be linked
to seasonal variation in other factors such as the incidence of infectious
agents.