This study examined the three-dimensional (3D) microarchitecture of regions
of the equine third metacarpal bone (McIII) commonly involved in distal co
ndylar fractures. Limbs were obtained from Thoroughbred horses (neonates to
age 24 years) destroyed for inoperable fractures and a variety of other co
nditions. Beams, blocks and sections were cut in the principal axes, some e
mbedded in PMMA and others examined unembedded, Several methods were used t
o study the 3D structure, including conventional and confocal optical micro
scopy, scanning electron microscopy (SEM) and radiography, The mineralised
articular cartilage tends to cleave in the sagittal plane. Proximal to the
subchondral bone, the main trabeculae are robust plates running in the sagi
ttal direction with less significant mediolateral connections. Small blood
vessel canals lie inside the sagittal plates, This structure gives maximum
strength and protection in the sagittal plane in which the bone rotates, bu
t offers minimal resistance to fracture propagation in this plane. The anat
omical course of the common distal condylar fractures of the third metacarp
al bones can be explained by underlying anisotropic structural features of
the mineralised tissues.