A total of 20 ventilation studies [16 with xenon-133 and four with techneti
um-99m diethylenetriamine pentaacetic acid (DTPA)] were performed in 11 pat
ients with suspected post-pneumonectomy bronchopleural fistulae, The findin
gs on the ventilation scan were correlated with bronchoscopy, taken as the
gold standard for purposes of comparison. The sensitivity and specificity f
or Xe-133 scans were 83% and 100% respectively, while the sensitivity for T
c-99m-DTPA aerosol studies was poor at 0%. Special techniques for optimal v
isualization of the fistulae are enumerated.