Reference typing report for complement receptor 1 (CR1)

Citation
Jm. Moulds et al., Reference typing report for complement receptor 1 (CR1), EXP CLIN IM, 15(4), 1998, pp. 291-294
Citations number
5
Categorie Soggetti
Molecular Biology & Genetics
Journal title
EXPERIMENTAL AND CLINICAL IMMUNOGENETICS
ISSN journal
02549670 → ACNP
Volume
15
Issue
4
Year of publication
1998
Pages
291 - 294
Database
ISI
SICI code
0254-9670(1998)15:4<291:RTRFCR>2.0.ZU;2-D
Abstract
A total of 100 Chinese blood donors (50 from Shen-Zhen and 50 from Taiwan) were studied by the participants in addition to 9 reference samples. A new nomenclature for the CR1 structural alleles was recommended by the particip ants which would use a numbering system, e.g. CR1*1. The structural allele frequencies in the Chinese were: CR1*1 (190 kD) 0.96, CR1*2 (220 kD) 0.03, CR1*3 (160 kD) 0.01 and CR1*4 (250 kD) 0.00, The HindIII expression polymor phism was also studied and the high expressing allele had a gene frequency of 0.71 while the low expressor gene frequency was 0.28. Erythrocyte copy n umbers were quantified and compared between laboratories with good correlat ion (R = 0.55-0.88), The mean (+/- SD) erythrocyte copy number was 463 (+/- 229) in the Taiwan donors and 446 (+/- 207) in the Mainland Chinese.