The selective ortho-methoxylation of pentafluorobenzoic acid - a new way to tetrafluorosalicylic acid and its derivatives

Authors
Bazyl', IT Kisil', SP Burgart, YV Saloutin, VI Chupakhin, ON
Citation
It. Bazyl' et al., The selective ortho-methoxylation of pentafluorobenzoic acid - a new way to tetrafluorosalicylic acid and its derivatives, J FLUORINE, 94(1), 1999, pp. 11-13
Citations number
11
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
JOURNAL OF FLUORINE CHEMISTRY
ISSN journal
00221139 → ACNP
Volume
94
Issue
1
Year of publication
1999
Pages
11 - 13
Database
ISI
SICI code
0022-1139(19990211)94:1<11:TSOOPA>2.0.ZU;2-8
Abstract
A simple and efficient preparation of tetrafluorosalicylic acid has been de veloped which involves a selective substitution of fluorine in pentafluorob enzoic acid with methoxyl group by magnesium methoxide. Tnc: synthesis of 2 ,6-dimethoxy-3,4,5-trifluorobenzoic acid, 4,5,6-trifluororesorcinol and its dimethoxy ether is described. (C) 1999 Elsevier Science S.A. All rights re served.