Cutaneous nerves of the palm were localized and quantitated by longitudinal
axis, proximity to the distal palmar crease, and tissue layer to identify
an incision that would avoid injury to the palmar branches of cutaneous ner
ves. Cadaveric palms (n = 10) harvested en bloc were fixed at physiologic t
ension and prepared using the celloidin method and hematoxylin-eosin staini
ng. The cutaneous nerves of the palm were counted and classified by their s
ize and location within each tissue layer and longitudinal axis as well as
by proximal, middle, and distal locations within each axis. The mean number
of large nerves identified within regions of the palm differed by tissue l
ayer and longitudinal axis but not by longitudinal location within axes. Th
e long/ring finger web space was characterized by the lowest innervation de
nsity; the index/long finger web space and ring finger axis were characteri
zed by the greatest innervation density. An incision in the long/ring finge
r web space 2 cm proximal to Kaplan's cardinal line should result in injury
to fewer nerves and reduce the incidence of painful neuromas during open c
arpal tunnel release. Copyright (C) 1999 by the American Society for Surger
y of the Hand.