Objective: The age at which a child becomes colonized with mutans streptoco
cci (MS) is important for understanding early childhood caries. The aim of
this study was to explore the relationship of age with MS colonization in i
nfants. Methods: Inner-city children (n=149) between the ages of 8 months a
nd 15 months, inclusive, who reportedly were still using a baby bottle, wer
e sampled for MS. Results: Evidence of MS colonization was seen as early at
10 months of age. For children 12 months old or younger (n=80), 25 percent
had detectable levels of MS;in the 15-month age group, 60 percent were col
onized Conclusion: This study suggests that prevention of MS colonization i
n some populations may need to be initiated prior to the child's first birt
hday.