The earliest references to the loss of nitrogen and phosphorus in activated
-sludge systems indicated an awareness, but no particular interest, in the
use of biological processes for the removal of nutrients. The development o
f extended-aeration processes in general, and of channel systems in particu
lar, intensified the interest in denitrification as a means of reducing nit
rogen in an effluent. Observations of simultaneous nitrification and denitr
ification led to the proposal of separate anoxic zones for optimal nitrogen
removal. The discovery that biological nitrogen and phosphorus removal cou
ld be synergistic, led to an explosion of processes, differing in all but t
he basic underlying biochemistry, for the removal of both nitrogen and phos
phorus. The development of computer models, to accurately describe the comp
lex and inter-related reactions, makes it possible to fully exploit biologi
cal systems to achieve cost-effective nutrient removal.