Wj. Hofste et al., DELIRIUM AND COGNITIVE DISORDERS AFTER CARDIAC OPERATIONS - RELATIONSHIP TO PREOPERATIVE AND INTRAOPERATIVE QUANTITATIVE ELECTROENCEPHALOGRAM, International journal of clinical monitoring and computing, 14(1), 1997, pp. 29-36
We examined the incidence of delirium and cognitive disorders after ca
rdiac operations and the related risk factors. The value of pre- and i
ntraoperative QEEG was determined. Using the Mini-Mental State Examina
tion and the Saskatoon Delirium Checklist, 321 patients were tested du
ring the immediate postoperative period. Forty-four patients (14%) sho
wed delirium, 68 (23%) cognitive disorders and 26 (9%) both. Significa
nt risk factors for the development of cognitive disorders were age gr
eater than or equal to 70 yr, female gender, duration of cardiopulmona
ry bypass greater than or equal to 2.5 h and aorta-cross-clamping > 70
min. Risk factors for delirium were age greater than or equal to 70 y
r, female gender and Hb < 5 mmol l(-1) intraoperatively. The preoperat
ive QEEG showed significant differences between the groups with and wi
thout a cognitive disorder, while the intraoperative QEEG showed signi
ficant differences between the groups with and without delirium. Diffe
rent risk factors for delirium and cognitive disorders are a possible
explanation for the controversies in the literature, where neuropsycho
logic complications were grouped together. A low intraoperative Hb is
an important risk factor for the development of delirium and can he tr
eated. The preoperative QEEG may have prognostic significance in the o
ccurrence of cognitive disorders, while the intraoperative QEEG may ha
ve prognostic significance in the occurrence of delirium.