We report a novel and simple application of skin conductance response (SCR)
testing for diagnosis of a new-onset iatrogenic Harlequin syndrome in an i
nfant. Isolated ipsilateral facial pallor, complicated by thermally induced
systemic sympathetic vasodilatation, and preferential lateral decubitus po
sitioning, mimics harlequin colour change. Correct diagnosis as Harlequin s
yndrome with facial sympathetic interruption was demonstrated by diminution
of SCR.