Pulmonary coccidioidomycosis is a rare cause of pulmonary nodules and respi
ratory infection in travellers to endemic areas. An Australian tourist suff
ered an acute respiratory illness while on holiday in Mexico. She subsequen
tly developed erythema nodosum and was noted to have a left pulmonary nodul
e on chest X-ray after return to Australia. The diagnosis of Coccidioides i
mmitis infection was established by histology and culture of the resected l
ung lesion. The patient made an uneventful recovery and received one month
of therapy with ketoconazole. Culture of the fungus took place under contro
lled Class 3 conditions. An unusual fungal infection in Australia, coccidio
idomycosis poses special risks to staff of microbiology laboratories.