The TISPR-1 integrated surface plasmon resonance (SPR) sensor has features
that make it ideal for use in a distributed sensor environment. This sensor
, combined with simple bio-films, is shown to be capable of a wide variety
of bio-assays. Data for a direct-binding assay for creatine kinase MB (CK-M
B), for a displacement assay for dinitrophenol-glycine (DNP-GLY) and a comp
etition assay for trinitrotoluene (TNT) are presented. Also, current and pr
ojected TISPR-1 sensor system limits of detection are discussed. (C) 1999 E
lsevier Science S.A. All rights reserved.