Basal cell carcinoma of the skin is one of the most common types of cancer.
Its natural history is one of local recurrence rather than metastatic spre
ad. Certain histologic features and primary tumor size seem to be risk fact
ors for metastases. The diagnosis of metastatic disease imparts a poor prog
nosis with a short median survival. Treatment is usually in the form of sys
temic chemotherapy wuith cisplatin-based combination described as most acti
ve agent.