Ab. Paspala et al., Exclusive CNS involvement by lymphomatoid granulomatosis in a 12-year-old boy: A case report, SURG NEUROL, 51(3), 1999, pp. 258-260
BACKGROUND Lymphomatoid granulomatosis [LYG] is an angiocentric, angiodestr
uctive disease at the higher grade end of the spectrum of angiocentric immu
noproliferative lesions. It primarily involves the lungs, but it may also i
nvolve several extrapulmonary sites including the central nervous system (C
NS), skin, and kidneys.
CASE DESCRIPTION Clinical presentation, radiology and treatment of LYG in a
12-year-old male child with multiple intracranial extraaxial lesions is de
scribed.
A 12-year-old boy presented with sudden onset of left focal motor seizures
with associated history of headache and vomiting. Computerized tomographic
scan of the brain suggested high-density, bilateral, parietal extraaxial le
sions. On magnetic resonance imaging, the lesions were iso- to hyperintense
on T1-weighted images and hyperintense on T2-weighted images. The lesions
were excised in two stages and histopathological examination confirmed the
diagnosis.
CONCLUSION LYG seldom involves the CNS exclusively. The present case demons
trates exclusive CNS involvement by LYG in a young boy. (C) 1999 by Elsevie
r Science Inc.