Heterocyclization of 4-trifluoroacetyl-2,3-dihydropyrroles with hydrazinesand amidines: A new access to trifluoromethylated pyrazoles and pyrimidines bearing a beta-aminoethyl side chain

Authors
Kawase, M Hirabayashi, M Saito, S Yamamoto, K
Citation
M. Kawase et al., Heterocyclization of 4-trifluoroacetyl-2,3-dihydropyrroles with hydrazinesand amidines: A new access to trifluoromethylated pyrazoles and pyrimidines bearing a beta-aminoethyl side chain, TETRAHEDR L, 40(13), 1999, pp. 2541-2544
Citations number
15
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
13
Year of publication
1999
Pages
2541 - 2544
Database
ISI
SICI code
0040-4039(19990326)40:13<2541:HO4WH>2.0.ZU;2-9
Abstract
Trifluoromethyl-substituted heterocycles have been prepared by condensation of the new 4-trifluoroacetyl-2,3-dihydropyrroles with hydrazines or amidin es as a bifunctional N-nucleophile with opening of the dihydropyrrole ring. (C) 1999 Elsevier Science Ltd. All rights reserved.