A new method for the synthesis of beta,gamma-unsaturated amides from allylic carbonate catalyzed by palladium in the presence of carbon monoxide and amine: Studies towards the total synthesis of antillatoxin

Authors
Loh, TP Cao, GQ Yin, Z
Citation
Tp. Loh et al., A new method for the synthesis of beta,gamma-unsaturated amides from allylic carbonate catalyzed by palladium in the presence of carbon monoxide and amine: Studies towards the total synthesis of antillatoxin, TETRAHEDR L, 40(13), 1999, pp. 2649-2652
Citations number
15
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
13
Year of publication
1999
Pages
2649 - 2652
Database
ISI
SICI code
0040-4039(19990326)40:13<2649:ANMFTS>2.0.ZU;2-T
Abstract
The reaction of alpha,beta-unsaturated carbonates was carried out in DMF in the presence of PdCl2/dppb (5 mol%), CO and L-alanine at 65 degrees C for 4 days to give the beta, gamma-unsaturated amide intermediate of antillatox in in good yield. (C) 1999 Published by Elsevier Science Ltd. All rights re served.