Protecting group controlled stereoselective alkylation of asymmetrized bis(hydroxymethyl)propanoates (BHYMP*)

Authors
Banfi, L Guanti, G
Citation
L. Banfi et G. Guanti, Protecting group controlled stereoselective alkylation of asymmetrized bis(hydroxymethyl)propanoates (BHYMP*), TETRAHEDR-A, 10(3), 1999, pp. 439-447
Citations number
11
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
3
Year of publication
1999
Pages
439 - 447
Database
ISI
SICI code
0957-4166(19990212)10:3<439:PGCSAO>2.0.ZU;2-Q
Abstract
The diastereoselective methylation of the enolates derived from some asymme trized bis(hydroxymethyl)propanoates (BHYMP*) has been studied. Good result s were achieved when one of the two hydroxymethyl groups was unprotected. T he induction was interpreted on the basis of an acyclic stereocontrol gover ned by stereoelectronic effects. (C) 1999 Elsevier Science Ltd. All rights reserved.