A permutation test is proposed for examining the significance of effec
ts in unreplicated factorial experiments. The procedure tests each eff
ect with a separate sampling distribution using a test statistic that
is equivalent to the optimal invariant decision rule of Birnbaum. The
proposed test is more flexible than other methods proposed for the sam
e situation because it requires no a priori assumptions regarding the
underlying distribution of the data nor does it impose any practical r
estriction on the number of potentially significant effects present.