Quality improvement requires reduction of undesired variation. Design
of experiments has become a useful tool for discovering such minimum v
ariance conditions, but most existing techniques require a large exper
imental effort involving replicated experiments. In this article we de
velop a method for significance testing of dispersion effects from unr
eplicated two-level fractional factorial experiments using principles
close to those for identifying location effects. The method provides a
n F-distributed test statistic and appears to be useful for identifica
tion of dispersion effects as early as the screening stage when fracti
onated unreplicated experiments are frequently employed.