Race is not independently associated with a positive prostate biopsy in men suspected of having prostate cancer

Objectives. To examine whether race is associated with the prostate biopsy result after controlling for other clinical factors in men undergoing ultra sound-guided prostate biopsy to evaluate an elevated serum prostate-specifi c antigen (PSA) or an abnormal digital rectal examination (DRE), or both. Methods. We reviewed the records of all men undergoing transrectal ultrasou nd-guided prostate biopsy at our facilities from January 1990 through March 1998. This included 1056 white men and 874 black men. Patient age, serum P SA, indication for prostate biopsy, and race were examined for association with the biopsy result. Results. Of the 1930 black and white men who underwent prostate biopsy, 639 (33%) had cancer, including 355 (41%) of 874 black men and 284 (27%) of 10 56 white men. Serum PSA, abnormal DRE, and age were independent predictors of a prostate biopsy being positive for cancer. Race was not an independent predictor of cancer being identified in the prostate biopsy. Conclusions. After controlling for PSA, DRE, and age, black men were not at an increased risk of a positive prostate biopsy relative to white men. Our data do not support the need to consider race when estimating the probabil ity that a man has prostate cancer. (C) 1999, Elsevier Science Inc. All rig hts reserved.