Recent immunization against measles does not interfere with the sero-response to yellow fever vaccine

In order to determine whether previous measles vaccination interferes with the sere-response to yellow fever vaccine, 294 children at nine months of a ge were randomly assigned to immunization with yellow fever vaccine at diff erent time intervals after measles vaccination. The seroconversion rate (SC R) and the log(10) geometric mean titer (GMT) for 17 DD yellow fever vaccin e at different intervals after Schwarz measles vaccination were: 1-6 days: SCR = 44/57 = 77%; GMT = 4.57; 7-13 days: SCR = 36/53 = 68%; GMT = 4.46; 14 -21 days: SCR = 55/65 = 85%; GMT = 4.46; 22-27 days: SCR = 41/54 = 76%; GMT = 4.41 and >28 days: SCR = 52/65 = 80%; GMT = 4.24 (p > 0.05). We conclude that recent immunization against measles does not interfere with the sere- response to yellow fever vaccine. (C) 1999 Elsevier Science Ltd. All rights reserved.