Korean nationwide surveillance of antimicrobial resistance of bacteria in 1997

Antimicrobial-resistant bacteria are known to be prevalent in tertiary-care hospitals in Korea. Twenty hospitals participated to this surveillance to determine the nationwide prevalence of resistance bacteria in 1997. Seven p er cent and 26% of Escherichia coli and Klebsiella pneumoniae were resistan t to 3rd-generation cephalosporin. Incp eased resistance rates, 19% of Acin etobacter baumannii to ampicillin/sulbactam, and 17% of Pseudomonas aerugin osa to imipenem, were noted. The resistance rate to fluoroquinolone rose to 24% in E. coli, 56% in A. baumannii and 42% in P. aeruginosa. Mean resista nce rates were similar in all hospital groups: about 17% of P. aeruginosa t o imipenem, 50% of Haemophilus influenzae to ampicillin, 70% of Staphylococ cus aureus to methicillin, and 70% of pneumococci to penicillin. In conclus ion, nosocomial pathogens and problem resistant organisms are prevalent in smaller hospitals too, indicating nosocomial spread is a significant cause of the increasing prevalence of resistant bacteria in Korea.