Antimicrobial resistance patterns of Bacteroides fragilis group organisms in Korea

Antimicrobial resistance patterns of 913 clinical isolates of Bacteroides f ragilis group organisms were monitored during an 8-year period in Korea. In general the resistance rates of the non-fragilis B. fragilis group species were higher than those of B. fragilis for all the drugs tested. The rate o f resistance to clindamycin remarkably increased and those to some beta-lac tam drugs such as piperacillin and cefotaxime also increased. No isolates,l ure found to be resistant to imipenem, metronidazole, or chloramphenicol. b eta-lactam and beta-lactamase inhibitor combinations and cefoxitin were mor e active than the other beta-lactams. Therefore, these agents may be consid ered when empirical selection of antimicrobial agents is required to treat severe anaerobic infections.