INDUCTION CHARACTERISTICS OF 2-PERCENT PROPOFOL IN CHILDREN

We have conducted a prospective, randomized study to evaluate the char acteristics of induction of anaesthesia in children with 2% propofol. Children were allocated to receive propofol 3 mg kg(-1) (group A), 4 m g kg(-1) (group B) or 5 mg kg(-1) (group C) of the 2% formulation. We observed a high incidence of spontaneous movements (90%) in group A an d an incidence of coughing of 70% in group C. Induction in group B was characterized by a short induction time, low incidence of spontaneous movements (20%), pain on injection (10%) and excellent conditions for manual ventilation.