A future prediction type artificial heart system

The demand of the biological system needs to be predicted to consider the q uality of life (QOL) of a patient with an artificial heart system. The purp ose of this study was the prediction of the imminent cardiac output and the predictive control for an artificial heart. For that purpose, autonomic ne rve information was applied in this study. Nervous sympathicus action poten tials were measured, and a prediction function of cardiac output was made u sing the sympathetic tone and preload and afterload measurement with multip le regression analysis. The predicted value showed significant correlation with the measured value after 2.9 s. Currently, however, long-term instrume ntation of the nervous sympathicus potential is difficult. Thus, hemodynami c fluctuations, which recently have attracted attention, were used in this study. A prediction function using the Mayer wave, which represented nervou s sympathicus, was determined. As a result, midterm prediction became possi ble. Furthermore, a measurement of the vagal nerve was used as a possible l ong-term prediction parameter. For long-term prediction, Hurst exponent ana lysis was used in this study. Vagal nerve discharges in the changing positi on showed alteration of longterm determination. In conclusion, the future p rediction control of an artificial heart takes shape using these prediction functions.