New quinoxaline 1,4-Di-N-oxides for treatment of tuberculosis

Authors
Sainz, Y Montoya, ME Martinez-Crespo, FJ Ortega, MA de Cerain, AL Monge, A
Citation
Y. Sainz et al., New quinoxaline 1,4-Di-N-oxides for treatment of tuberculosis, ARZNEI-FOR, 49(1), 1999, pp. 55-59
Citations number
16
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
ISSN journal
00044172 → ACNP
Volume
49
Issue
1
Year of publication
1999
Pages
55 - 59
Database
ISI
SICI code
0004-4172(199901)49:1<55:NQ1FTO>2.0.ZU;2-L
Abstract
Some quinoxaline 1,4-di-N-oxides derivatives with very different substituen ts in 2, 3, 6 and 7 positions have been synthesized in order to obtain new hypoxia selective agents. Some of these products have been tested as antitu berculosis agents and very interesting results have been obtained from the first screening.