An eight-year-old, FIV-positive, domestic shorthaired cat presented with we
ight loss and progressive neurological signs. Thoracic radiographs showed m
ultiple pulmonary nodules and the cat was euthanased. Squash preparations o
f the lung lesions were made at necropsy and were cytologically consistent
with carcinoma. Histologically, the cat had pulmonary and cerebellar toxopl
asmosis. Tachyzoites were difficult to demonstrate in the lung lesions both
histologically and cytologically. This case demonstrates the difficulties
in ante-mortem diagnosis of toxoplasmosis in the cat.