The current status of tardive dystonia

Citation
Ya. Adityanjee,"aderibigbe et al., The current status of tardive dystonia, BIOL PSYCHI, 45(6), 1999, pp. 715-730
Citations number
162
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BIOLOGICAL PSYCHIATRY
ISSN journal
00063223 → ACNP
Volume
45
Issue
6
Year of publication
1999
Pages
715 - 730
Database
ISI
SICI code
0006-3223(19990315)45:6<715:TCSOTD>2.0.ZU;2-0
Abstract
Tardive dystonia (TDt), a persistent dystonia associated with exposure to n eurolept ic drugs, is an uncommon disorder. It differs from tardive dyskine sia (TDk) in epidemiology, clinical features, risk factors, pathophysiology , course, prognosis, and treatment outcome. TDt seems to develop faster and is more painful, distressing, and disabling than tardive dyskinesia. In th is article, evidence is reviewed on the face, descriptive, construct and pr edictive validity of this iatrogenic complication of antipsychotic drugs. I t is suggested that TDt should not be lumped together with TDk. It deserves a separate nosological status as an independent diagnostic category. The s ubclassification of TDt into various subtypes based on coexistence of other movement disorders is suggested. (C) 1999 Society of Biological Psychiatry .