Mood disorders are prevalent and serious disorders in children and adolesce
nts, often causing substantial difficulties in school performance and socia
l relationships. Although the criteria for major depressive disorder are th
e same for children and adolescents as for adults, some challenges exist in
ascertaining the diagnosis. For example, children often have difficulty in
expressing or recalling information regarding their disorder; therefore, m
ultiple informants (usually parents) must often be used to obtain the infor
mation. In addition, comorbid diagnoses are common in early onset depressio
n, making diagnosis more difficult. However, depression is diagnosable in c
hildren and adolescents.
The treatment of depression in this population is multi-modal, including th
e child, parents and school, and is aimed at shortening the episode of depr
ession. Treatment, which is individualised based on need, may include psych
otherapy, family therapy or education, and pharmacological treatment. Selec
tive serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitors are generall
y the first line of pharmacological treatment in children and adolescents,
as they are well tolerated and appear to have fewer adverse effects than an
tidepressants.
As with adults, the majority of children and adolescents with depression do
recover within 1 to 2 years; however, recurrence is common. In fact, the r
ecurrence rate is somewhat higher in children and adolescents than in adult
s. Unfortunately, little research has been done regarding maintenance treat
ment in children and adolescents. Further research in this area is needed t
o determine the most effective duration of medication treatment.