Xylazine sedation antagonized with tolazoline

Authors
Thurmon, JC Sarr, R Denhart, JW
Citation
Jc. Thurmon et al., Xylazine sedation antagonized with tolazoline, COMP CONT E, 21(1), 1999, pp. S11-S19
Citations number
41
Categorie Soggetti
Veterinary Medicine/Animal Health
Journal title
COMPENDIUM ON CONTINUING EDUCATION FOR THE PRACTICING VETERINARIAN
ISSN journal
01931903 → ACNP
Volume
21
Issue
1
Year of publication
1999
Supplement
S
Pages
S11 - S19
Database
ISI
SICI code
0193-1903(199901)21:1<S11:XSAWT>2.0.ZU;2-G
Abstract
Physiologic alterations induced by xylazine depend on the dose, rate, and r oute of administration and are influenced by the concomitant administration of other classes of drugs. When these factors are appropriately considered , alpha(2)-adrenoceptor agonists are safe drugs for inducing narcosis, anal gesia, and muscle relaxation in healthy fasted ruminants. Tolazoline has pr oven to be a safe, effective antagonist for xylazine-induced sedation and o ther actions when the proper dose is administered.