This paper summarizes the assessment of risks to fishes in the Clinch River
Operable Unit due to contaminants released by the U.S. Department of Energ
y's activities on its Oak Ridge Reservation in Tennessee. This paper focuse
s on the most contaminated area, the Poplar Creek (PC) embayment. The asses
sment is of interest because of its use of five distinct lines of evidence:
fish community surveys, fish body burdens, toxicity tests of ambient water
s, suborganismal bioindicators, and single chemical toxicity tests. None of
these lines of evidence provided unambiguous evidence of a significant ris
k, but the surveys indicated that the fish community in PC was depauperate,
polychlorinated biphenyl body burdens may have been at toxic levels in cat
fish, one of the three tests of ambient water showed clear toxicity, some o
f the indicators were indicative of toxic effects, and concentrations that
have been toxic in the laboratory were detected periodically. Interpretatio
n was further complicated by upstream contamination of both the Clinch Rive
r and PC. The risk characterization was performed by evaluating each line o
f evidence separately and then weighing the evidence using an ecoepidemiolo
gical approach.