R. Otsu, Outbreaks of gastroenteritis caused by SRSVs from 1987 to 1992 in Kyushu, Japan: Four outbreaks associated with oyster consumption, EUR J EPID, 15(2), 1999, pp. 175-180
Citations number
33
Categorie Soggetti
Envirnomentale Medicine & Public Health","Medical Research General Topics
From 1987 to 1992, 18 outbreaks of acute non-bacterial gastroenteritis occu
rred in Kyushu district. The most common symptoms were diarrhea, vomiting,
nausea and abdominal cramp. Small round structured viruses (SRSVs) were det
ected in 52 (44.8%) of 116 stool samples from 17 outbreaks by the electron
microscopy (EM) method, and a significant increase in the antibody level wa
s noted in 42 (80.7%) of 52 paired serum samples from 12 outbreaks by the i
mmune electron microscopy (IEM) method and in 18 (51.4%) of 35 samples from
8 outbreaks by the western blot (WB) method. However, according to the WE
method, antigen-antibody reaction was not observed to reference antigen str
ips (SRSV-9/Tokyo 86-510, 63 kDa) in three of the 8 outbreaks, The detected
virus was regarded as an etiologic agent for these outbreaks. In four of 5
outbreaks which appeared associated with eating raw oysters, there was a c
lose relation between SRSV infection and consumption of raw oysters.