Expression of glutathione S-transferases (GSTs) in Fasciola gigantica derived from three hosts (cattle, water buffaloes and donkeys)

Authors
El-Gaysh, AA Barrett, J Brophy, PM
Citation
Aa. El-gaysh et al., Expression of glutathione S-transferases (GSTs) in Fasciola gigantica derived from three hosts (cattle, water buffaloes and donkeys), HELMINTHOL, 36(1), 1999, pp. 5-8
Citations number
13
Categorie Soggetti
Animal Sciences
Journal title
HELMINTHOLOGIA
ISSN journal
04406605 → ACNP
Volume
36
Issue
1
Year of publication
1999
Pages
5 - 8
Database
ISI
SICI code
0440-6605(199903)36:1<5:EOGS(I>2.0.ZU;2-K
Abstract
Glutathione S-transferase (GSTs) from F, gigantica collected from cattle, w ater buffaloes and donkeys have been partially purified by glutathione affi nity chromatography. F. gigantica expresses multiple forms of GST with simi lar SDS-PAGE mobility patterns as F. hepatica. The only indication in this study of why F. gigantica GSTs are less protective than F. hepatica GSTs in challenge infections was a six fold less overall GST specific activity in the tropical fluke.