Synthesis and fungicidal activity of 3-aryl-2-(4 '-aryl thiazol-2 '-ylaminomethyl)quinazol-4 (3H)-ones

Citation
Jm. Pattanaik et al., Synthesis and fungicidal activity of 3-aryl-2-(4 '-aryl thiazol-2 '-ylaminomethyl)quinazol-4 (3H)-ones, I J CHEM B, 37(12), 1998, pp. 1304-1306
Citations number
12
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
ISSN journal
03764699 → ACNP
Volume
37
Issue
12
Year of publication
1998
Pages
1304 - 1306
Database
ISI
SICI code
0376-4699(199812)37:12<1304:SAFAO3>2.0.ZU;2-Y
Abstract
A series of 3-aryl-2-(4'-aryl thiazol-2'-ylaminomethyl) quinazol-4(3H)-ones 3a-p have been prepared by condensing 3-aryl-2-chlnromethylquinazol-4(3H)- ones with 2-amino-4-substituted phenylthiazoles. Another group of 3-aryl-6, 8-dibromo-2-(4'-arylthiazol-2'-ylaminomethyl) quinazol-4 (3H)ones 3q-gg ha ve also been synthesized from 3-aryl-6, 8-dibromo-2-chloromethylquinazol-4( 3H)-ones and 2-amino-4-substituted phenylthiazoles in the same manner, The prepared compounds have been characterised by spectral data. Their antifung al activity has also been determined.