Characterization of an immunogenic glycocalyx on the surfaces of Cryptosporidium parvum oocysts and sporozoites

Authors
Nanduri, J Williams, S Aji, T Flanigan, TP
Citation
J. Nanduri et al., Characterization of an immunogenic glycocalyx on the surfaces of Cryptosporidium parvum oocysts and sporozoites, INFEC IMMUN, 67(4), 1999, pp. 2022-2024
Citations number
16
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
67
Issue
4
Year of publication
1999
Pages
2022 - 2024
Database
ISI
SICI code
0019-9567(199904)67:4<2022:COAIGO>2.0.ZU;2-T
Abstract
Ruthenium red staining of Cryptosporidium parvum oocysts revealed the prese nce of a carbohydrate matrix on their outer bilayers that is characteristic of a glycocalyx. Surface labeling of intact oocysts identified material of high molecular weight (>10(6)) that reacted positively with sera from cryp tosporidium-infected patients and with immunoglobulin A monoclonal antibodi es.