Objective: To assess the relationship between poverty and mental illne
ss in order to simulate debate on future international cooperation pro
grams in mental health. Method: Epidemiological data in the internatio
nal literature addressing the issue of material poverty as a risk fact
or for the development of mental illness and as a prognostic factor fo
r the outcome of mental illness were reviewed. Results: The internatio
nal literature reviewed supports the notion that material poverty is a
risk factor for a negative outcome among mentally ill people. In addi
tion, preliminary epidemiological data suggest that service-related va
riables may be determinants of outcome of mental illnesses. In our vie
w, cooperation with developing countries is a great opportunity to eva
luate mental health services in a natural setting. Conclusions: A new
generation of programs for international cooperation in mental health
is needed, in which knowledge and technology transfer is based on a se
rvice-research attitude. Attention should be focused on variables rela
ted to the poverty of services that might be linked to the course and
outcome of mental illnesses.