The management of acute poisoning remains an important part of accident and
emergency (A&E) care. Three gastric decontamination procedures have been w
idely used: gastric lavage, ipecac, and activated charcoal. Their role has
recently been reviewed and position statements developed by working groups
of the American Academy of Clinical Toxicology and the European Association
of Poisons Centres and Clinical Toxicologists. These have important implic
ations for A&E, as they indicate that activated charcoal is now the agent o
f choice for most poisons, but that in most situations it is probably only
effective if given within an hour of overdose. Ipecac is effectively obsole
te and gastric lavage has a narrow range of indications, principally for po
tentially serious amounts of agents not adsorbed by charcoal. Protocols for
care of overdose patients should be modified accordingly.