Rm. Mohareb et al., Reaction of carbon disulfide with cyanoacetic acid hydrazide: Novel synthesis of thiazole and thiazolo[4,5-c]pyrazole, J CHEM R-S, (1), 1999, pp. 10
The reaction of cyanoacetic acid hydrazide with carbon disulfide in basic d
imethylformamide afforded the potassium thiocarbamate 2 which underwent rea
dy heterocyclization upon its reaction with alpha-haloketones to give the t
hiazole derivatives 4 and 23.