Ha. Chung et al., Retro-ene reaction. V. Functionalization of 4,5-dihalopyridazin-6-ones using 1-hydroxymethyl-4,5-dihalopyridazin-6-ones as 1-O, 3-N, 5-O ene-adducts, J HETERO CH, 36(1), 1999, pp. 277-281
Functionalization of 1-hydroxymethyl-4,5-dihalopyridazin-6-ones via a retro
-ene reaction with some nucleophiles gave regio selectively only 5-halo-4-s
ubstitutedpyridazin-6-ones.