We report on a patient with hypokalaemia and severe ventricular tachycardia
of torsades de pointes type which turned out to be caused by an apparent m
ineralocorticoid excess syndrome associated with liquorice consumption. The
patient, a 44-year-old woman, attended the hospital because of irregular h
eart rhythm and she displayed repeated episodes of life-threatening torsade
s de pointes ventricular tachycardia. The initial serum potassium was low:
2.3 mmol L-1. The patient was treated with potassium and magnesium infusion
s, and the dysrhythmias eventually ceased. Endocrinological investigations
showed no indication of Gushing's syndrome or hyperaldosteronism. After som
e time it became dear that the patient had ingested moderately large amount
s of liquorice every day for 4 months. After the patient stopped this habit
the hypokalaemia and dysrhythmias did not recur and after more than 1 year
there are no signs of cardiac illness.