Life-threatening ventricular tachycardia due to liquorice-induced hypokalaemia

Citation
Jw. Eriksson et al., Life-threatening ventricular tachycardia due to liquorice-induced hypokalaemia, J INTERN M, 245(3), 1999, pp. 307-310
Citations number
8
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
JOURNAL OF INTERNAL MEDICINE
ISSN journal
09546820 → ACNP
Volume
245
Issue
3
Year of publication
1999
Pages
307 - 310
Database
ISI
SICI code
0954-6820(199903)245:3<307:LVTDTL>2.0.ZU;2-K
Abstract
We report on a patient with hypokalaemia and severe ventricular tachycardia of torsades de pointes type which turned out to be caused by an apparent m ineralocorticoid excess syndrome associated with liquorice consumption. The patient, a 44-year-old woman, attended the hospital because of irregular h eart rhythm and she displayed repeated episodes of life-threatening torsade s de pointes ventricular tachycardia. The initial serum potassium was low: 2.3 mmol L-1. The patient was treated with potassium and magnesium infusion s, and the dysrhythmias eventually ceased. Endocrinological investigations showed no indication of Gushing's syndrome or hyperaldosteronism. After som e time it became dear that the patient had ingested moderately large amount s of liquorice every day for 4 months. After the patient stopped this habit the hypokalaemia and dysrhythmias did not recur and after more than 1 year there are no signs of cardiac illness.