THE NEW NON-HIV ANTIVIRALS AND ANTIFUNGALS - REVIEW AND ASSESSMENT FOR THE FORMULARY .2.

In this article, part two of a two-part series, we summarize informati on crucial to the evaluation of some of the many new non-HN antivirals and antifungals for formulary consideration. The comparative spectrum of antimicrobial activity is reviewed, as are significant differences in the toxicity and pharmacokinetic profiles between new and older ag ents. We also provide our assessment of the role of each of these new agents in the management of selected infectious diseases. Appropriate use of new broad-spectrum antivirals and, antifungals is crucial to at tempts to diminish the impact of infections and minimize the emergence of drug-resistant pathogens.