Cp. Kurtzman et Cj. Robnett, IDENTIFICATION OF CLINICALLY IMPORTANT ASCOMYCETOUS YEASTS BASED ON NUCLEOTIDE DIVERGENCE IN THE 5'-END OF THE LARGE-SUBUNIT (26S) RIBOSOMAL DNA GENE, Journal of clinical microbiology, 35(5), 1997, pp. 1216-1223
Clinically important species of Candida and related organisms were com
pared for extent of nucleotide divergence in the 5' end of the large-s
ubunit (26S) ribosomal DNA (rDNA) gene;This rDNA region is sufficientl
y variable to allow reliable separation of all known clinically signif
icant yeast species, Of the 204 described species examined, 21 appeare
d to be synonyms of previously described organisms, Phylogenetic relat
ionships among the species are presented.