The objective of this study was to correlate contrast-enhanced computed tom
ography images of noncalcified hamartomas with histologic specimens to find
specific computed tomography enhancement patterns. Over 4 years, 30 noncal
cified hamartomas were surgically resected. Enhanced computed tomography im
ages of these hamartomas were reviewed and correlated with histologic findi
ngs. Contrast-enhancing septa were present in 24 of 30 hamartomas (80%). Fi
ve hamartomas (15%) showed a nonspecific enhancement pattern. The presence
of an air bronchogram was a rare finding (5%). Comparison between computed
tomography images and pathologic specimens showed that areas with less enha
ncement corresponded to cartilagineus tissue, and enhancing septa correspon
ded to loose connective tissue within the cartilagineus core. The rare find
ing of an air bronchogram corresponded to bronchial epithelium within carti
lagineus tissue.