CURCACYCLINE-B, A CYCLIC NONAPEPTIDE FROM JATROPHA-CURCAS ENHANCING ROTAMASE ACTIVITY OF CYCLOPHILIN

Authors
AUVIN C BARAGUEY C BLOND A LEZENVEN F POUSSET JL BODO B
Citation
C. Auvin et al., CURCACYCLINE-B, A CYCLIC NONAPEPTIDE FROM JATROPHA-CURCAS ENHANCING ROTAMASE ACTIVITY OF CYCLOPHILIN, Tetrahedron letters, 38(16), 1997, pp. 2845-2848
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
16
Year of publication
1997
Pages
2845 - 2848
Database
ISI
SICI code
0040-4039(1997)38:16<2845:CACNFJ>2.0.ZU;2-5
Abstract
The structure of curcacycline B (1), a cyclic nonapeptide isolated fro m Jatropha curcas latex was elucidated by combination of chemical degr adation, LSIMS data and 2D NMR experiments. Curcacycline B was shown t o enhance the rotamase activity of human cyclophilin B. (C) 1997 Publi shed by Elsevier Science Ltd.